Detalhe da pesquisa
1.
PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.
Mol Cell
; 83(16): 2991-3009.e13, 2023 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567175
2.
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Nature
; 618(7963): 159-168, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37225977
3.
The cytotoxic T cell proteome and its shaping by the kinase mTOR.
Nat Immunol
; 17(1): 104-12, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26551880
4.
The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system.
J Cell Sci
; 136(6)2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36825945
5.
Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells.
Immunity
; 45(3): 685-700, 2016 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27566939
6.
PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.
Mol Cell
; 68(3): 566-580.e10, 2017 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29056325
7.
Association between Subjective Cognitive Complaints and Incident Functional Impairment in Parkinson's Disease.
Mov Disord
; 39(4): 706-714, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38318953
8.
The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output.
Mol Cell
; 58(3): 453-67, 2015 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25866244
9.
Understanding the Relationship Between Perseveration, Comorbid Behavioral Symptoms, Motor Decline, Functional Decline, and Self-report Accuracy in Huntington Disease Can Help Inform Clinical Practice.
Cogn Behav Neurol
; 36(2): 93-99, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36633581
10.
Somatoform Symptoms in Parkinson Disease.
Cogn Behav Neurol
; 35(4): 255-262, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36201624
11.
The Parkinson's disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P3.
J Cell Sci
; 132(20)2019 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31540955
12.
Tominersen in Adults with Manifest Huntington's Disease.
N Engl J Med
; 389(23): 2203-2205, 2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38055260
13.
The choice not to undergo genetic testing for Huntington disease: Results from the PHAROS study.
Clin Genet
; 96(1): 28-34, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31093973
14.
Long-term safety and efficacy of deutetrabenazine for the treatment of tardive dyskinesia.
J Neurol Neurosurg Psychiatry
; 90(12): 1317-1323, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31296586
15.
cAMP Signaling of Adenylate Cyclase Toxin Blocks the Oxidative Burst of Neutrophils through Epac-Mediated Inhibition of Phospholipase C Activity.
J Immunol
; 198(3): 1285-1296, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28039302
16.
Structure of lipid kinase p110ß/p85ß elucidates an unusual SH2-domain-mediated inhibitory mechanism.
Mol Cell
; 41(5): 567-78, 2011 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21362552
17.
Mechanism of activation of SGK3 by growth factors via the Class 1 and Class 3 PI3Ks.
Biochem J
; 475(1): 117-135, 2018 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29150437
18.
In B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signaling.
Proc Natl Acad Sci U S A
; 113(38): 10571-6, 2016 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27601656
19.
The Calcaneal Crescent in Patients With and Without Plantar Fasciitis: An Ankle MRI Study.
AJR Am J Roentgenol
; 211(5): 1075-1082, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30160979
20.
Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis.
Proc Natl Acad Sci U S A
; 111(1): 155-60, 2014 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24367090